{"id":18,"date":"2025-09-18T16:41:57","date_gmt":"2025-09-18T07:41:57","guid":{"rendered":"http:\/\/localhost:8888\/?page_id=18"},"modified":"2025-11-04T12:23:30","modified_gmt":"2025-11-04T03:23:30","slug":"spermidine","status":"publish","type":"page","link":"https:\/\/biopqq.jp\/yeast\/spermidine\/","title":{"rendered":"\u6e05\u9152\u9175\u6bcd\u30a8\u30ea\u30aa\u30f3\u00aeSP"},"content":{"rendered":"\n<div class=\"wp-block-group section\"><div class=\"wp-block-group__inner-container\">\n<div class=\"wp-block-group section\"><div class=\"wp-block-group__inner-container\">\n<h3 class=\"wp-block-heading\">1.\u3000\u6ce8\u76ee\u306e\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u6210\u5206\u300c\u30b9\u30da\u30eb\u30df\u30b8\u30f3\u300d\u3092<br>\u52b9\u679c\u7684\u306b\u6442\u53d6\u3067\u304d\u308b\u9175\u6bcd<\/h3>\n\n\n\n<p>\u30a8\u30ea\u30aa\u30f3\u00aeSP\u306f\u3001\u65e5\u672c\u9152\u306e\u88fd\u9020\u306b\u7528\u3044\u3089\u308c\u3066\u304d\u305f\u9175\u6bcd\u3092\u3001\u4e09\u83f1\u30ac\u30b9\u5316\u5b66\u304c\u72ec\u81ea\u306e\u80b2\u7a2e\u6280\u8853\u306b\u3088\u3063\u3066\u958b\u767a\u3057\u305f\u9175\u6bcd\u3067\u3059\u3002\u9175\u6bcd\u7531\u6765\u306e\u30d3\u30bf\u30df\u30f3\u3001\u30a2\u30df\u30ce\u9178\u3001\u30df\u30cd\u30e9\u30eb\u306a\u3069\u306e\u6804\u990a\u6210\u5206\u3092\u8c4a\u5bcc\u306b\u542b\u3080\u3060\u3051\u3067\u306a\u304f\u3001\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u6210\u5206\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u300c\u30b9\u30da\u30eb\u30df\u30b8\u30f3\u300d\u3092\u591a\u304f\u542b\u6709\u3057\u3066\u3044\u308b\u70b9\u304c\u5927\u304d\u306a\u7279\u9577\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large is-resized size-full\"><img loading=\"lazy\" src=\"http:\/\/haw1009ftt3g.smartrelease.jp\/yeast\/wp-content\/uploads\/2025\/10\/\u30a8\u30ea\u30aa\u30f3SP\u2467-1.jpg\" alt=\"\" class=\"wp-image-48\" width=\"401\" height=\"368\" srcset=\"https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/\u30a8\u30ea\u30aa\u30f3SP\u2467-1.jpg 801w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/\u30a8\u30ea\u30aa\u30f3SP\u2467-1-300x276.jpg 300w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/\u30a8\u30ea\u30aa\u30f3SP\u2467-1-768x706.jpg 768w\" sizes=\"(max-width: 401px) 100vw, 401px\" \/><\/figure>\n\n\n\n<p>\u30b9\u30da\u30eb\u30df\u30b8\u30f3\u306f\u30dd\u30ea\u30a2\u30df\u30f3\u306e\u4e00\u7a2e\u3067\u3001\u52a0\u9f62\u3068\u3068\u3082\u306b\u8840\u4e2d\u6fc3\u5ea6\u304c\u4f4e\u4e0b\u3059\u308b\u3068\u3044\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u7d0d\u8c46\u306a\u3069\u306e\u767a\u9175\u98df\u54c1\u306b\u542b\u307e\u308c\u3001\u98df\u54c1\u304b\u3089\u6442\u53d6\u3059\u308b\u3053\u3068\u3082\u3067\u304d\u307e\u3059\u304c\u3001\u305d\u306e\u91cf\u306f\u591a\u304f\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" width=\"1024\" height=\"483\" src=\"http:\/\/haw1009ftt3g.smartrelease.jp\/yeast\/wp-content\/uploads\/2025\/10\/10-1024x483.jpg\" alt=\"\" class=\"wp-image-44\" srcset=\"https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/10-1024x483.jpg 1024w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/10-300x141.jpg 300w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/10-768x362.jpg 768w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/10-1536x724.jpg 1536w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/10-2048x965.jpg 2048w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/10-1200x566.jpg 1200w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/10-1980x933.jpg 1980w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30a8\u30ea\u30aa\u30f3\u00aeSP\u306f\u30012.0 mg\/g\uff082000\u00b5g\/g\uff09\u4ee5\u4e0a\u306e\u9ad8\u6fc3\u5ea6\u306e\u30b9\u30da\u30eb\u30df\u30b8\u30f3\u3092\u542b\u3093\u3067\u304a\u308a\u3001\u7d0d\u8c46\u306b\u542b\u307e\u308c\u3066\u3044\u308b56.1 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class=\"wp-block-group section\"><div class=\"wp-block-group__inner-container\">\n<h3 class=\"wp-block-heading\">\uff12\uff0e\u30b9\u30da\u30eb\u30df\u30b8\u30f3\u306e\u5065\u5eb7\u3078\u306e\u5f71\u97ff<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">\u2460 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class=\"wp-block-image size-large\"><img loading=\"lazy\" width=\"1024\" height=\"663\" src=\"http:\/\/haw1009ftt3g.smartrelease.jp\/yeast\/wp-content\/uploads\/2025\/10\/11-1024x663.jpg\" alt=\"\" class=\"wp-image-45\" srcset=\"https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/11-1024x663.jpg 1024w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/11-300x194.jpg 300w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/11-768x497.jpg 768w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/11-1536x994.jpg 1536w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/11-1200x777.jpg 1200w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/11-1980x1281.jpg 1980w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/11.jpg 2001w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h4 class=\"wp-block-heading\">\u2461 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\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0<\/h4>\n\n\n\n<p>\u76ae\u819a\u306e\u65b0\u9673\u4ee3\u8b1d\u3084\u9aea\u306e\u6bdb\u306e\u6210\u9577\u306a\u3069\u3001\u7f8e\u5bb9\u9762\u306b\u304a\u3044\u3066\u3082\u7d30\u80de\u306e\u5897\u6b96\u3084\u4fee\u5fa9\u306f\u91cd\u8981\u3067\u3059\u3002\u30b9\u30da\u30eb\u30df\u30b8\u30f3\u306b\u3088\u308b\u7d30\u80de\u5897\u6b96\u306e\u6d3b\u6027\u5316\u306f\u3001\u808c\u3084\u9aea\u306e\u5065\u5eb7\u7dad\u6301\u306b\u3082\u8ca2\u732e\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n<\/div><\/div>\n\n\n\n<!--split-->\n\n\n\n<div class=\"wp-block-group section\"><div class=\"wp-block-group__inner-container\">\n<h3 class=\"wp-block-heading\">\u30d2\u30c8\u81e8\u5e8a\u8a66\u9a13\uff08\u81ea\u793e\u30c7\u30fc\u30bf\uff09<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">\u2460 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class=\"wp-block-image size-large\"><img loading=\"lazy\" width=\"1024\" height=\"842\" src=\"https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/11\/\u4fee\u6b63\u72482025-07_\u56f312-1024x842.jpg\" alt=\"\" class=\"wp-image-70\" srcset=\"https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/11\/\u4fee\u6b63\u72482025-07_\u56f312-1024x842.jpg 1024w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/11\/\u4fee\u6b63\u72482025-07_\u56f312-300x247.jpg 300w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/11\/\u4fee\u6b63\u72482025-07_\u56f312-768x632.jpg 768w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/11\/\u4fee\u6b63\u72482025-07_\u56f312-1536x1263.jpg 1536w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/11\/\u4fee\u6b63\u72482025-07_\u56f312.jpg 2001w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption>\u203b\u7b4b\u8089\u91cf\u306e\u8a55\u4fa1\u306f\u5468\u6ce2\u6570\u4f53\u7d44\u6210\u8a08\u306b\u3088\u308b\u6e2c\u5b9a\u3067\u884c\u3044\u307e\u3057\u305f\u3002<\/figcaption><\/figure>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u7d50\u679c\u306f\u3001\u30a8\u30ea\u30aa\u30f3\u00aeSP\u304c\u5065\u5e38\u306a\u4e2d\u9ad8\u5e74\u7537\u6027\u306e\u904b\u52d5\u306b\u3088\u308b\u7b4b\u8089\u91cf\u5897\u52a0\u52b9\u679c\u3092\u9ad8\u3081\u308b\u4f5c\u7528\u3092\u6301\u3064\u53ef\u80fd\u6027\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u52a0\u9f62\u3084\u75be\u60a3\u306b\u3088\u308a\u7b4b\u529b\u4f4e\u4e0b\u304c\u8d77\u3053\u308b\u30b5\u30eb\u30b3\u30da\u30cb\u30a2\u306a\u3069\u306e\u5bfe\u7b56\u306f\u793e\u4f1a\u8ab2\u984c\u3068\u306a\u3063\u3066\u3044\u308b\u305f\u3081\u3001\u52a0\u9f62\u306b\u3088\u308b\u904b\u52d5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3092\u4e88\u9632\u3059\u308b\u98df\u54c1\u3068\u3057\u3066\u306e\u671f\u5f85\u3082\u9ad8\u307e\u308a\u307e\u3059\u3002<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group section\"><div class=\"wp-block-group__inner-container\">\n<h3 class=\"wp-block-heading\">\u7d30\u80de\u5b9f\u9a13\uff08\u81ea\u793e\u30c7\u30fc\u30bf\uff09<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">\u7b4b\u82bd\u7d30\u80de\u306e\u5897\u6b96\u3092\u4fc3\u9032<\/h4>\n\n\n\n<p>\u30de\u30a6\u30b9\u306e\u7b4b\u8089\u304b\u3089\u53d6\u308a\u51fa\u3057\u3066\u57f9\u990a\u3057\u305f\u7b4b\u82bd\u7d30\u80de\uff08\u7b4b\u8089\u3092\u69cb\u6210\u3059\u308b\u7d30\u80de\u306e\u5143\u3068\u306a\u308b\u7d30\u80de\uff09\u306b\u3001\u30a8\u30ea\u30aa\u30f3\u00aeSP\u3092\u52a0\u3048\u3066\u57f9\u990a\u3057\u305f\u3068\u3053\u308d\u3001\u7121\u6dfb\u52a0\u6642\u3068\u6bd4\u3079\u3066\u7b4b\u7ba1\u7d30\u80de\u306e\u5272\u5408\u304c\u591a\u304f\u306a\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002\u7b4b\u7ba1\u7d30\u80de\u306f\u3055\u3089\u306b\u6210\u719f\u3057\u3066\u96c6\u5408\u3059\u308b\u3053\u3068\u3067\u7b4b\u7e4a\u7dad\u3092\u5f62\u6210\u3057\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306b\u3001\u30a8\u30ea\u30aa\u30f3\u00aeSP\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u7b4b\u8089\u91cf\u304c\u5897\u52a0\u3057\u305f\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u4e00\u7aef\u304c\u660e\u3089\u304b\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" width=\"1024\" height=\"677\" src=\"http:\/\/haw1009ftt3g.smartrelease.jp\/yeast\/wp-content\/uploads\/2025\/10\/13-1024x677.jpg\" alt=\"\" class=\"wp-image-47\" srcset=\"https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/13-1024x677.jpg 1024w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/13-300x198.jpg 300w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/13-768x508.jpg 768w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/13-1536x1016.jpg 1536w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/13-2048x1355.jpg 2048w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/13-1200x794.jpg 1200w, https:\/\/biopqq.jp\/yeast\/wp-content\/uploads\/2025\/10\/13-1980x1310.jpg 1980w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption>\u203b\u30df\u30aa\u30b7\u30f3\u91cd\u93ae\u9762\u7a4d\u5360\u6709\u7387\u304c\u9ad8\u3044\u307b\u3069\u3001\u7b4b\u7ba1\u7d30\u80de\u306e\u5272\u5408\u304c\u5897\u52a0\u3057\u305f\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/figcaption><\/figure>\n<\/div><\/div>\n\n\n\n<!--split-->\n\n\n\n<p>1) \u4e95\u90e8\u660e\u5e83(2004)\u300c\u767a\u9175\u98df\u54c1\u306b\u542b\u307e\u308c\u308b\u30a2\u30df\u30f3\u985e\u300d\u6771\u4eac\u5065\u5b89\u7814\u30bb\u5e74\u583155, p.13-22<\/p>\n\n\n\n<p>2) Madeo F,et.al.,Spermidine in health and disease.Science. 2018 Jan 26;359(6374):eaan2788.doi:10.1126\/science.aan2788<\/p>\n\n\n\n<p>3) Al-Habsi M,et al.Spermidine activates mitochondrial trifunctional proteinand improves antitumor immunity in mice.Science.2022;378(6618):eabj3510.doi:10.1126\/science.abj3510<\/p>\n\n\n\n<p>4) Schroeder S,et al.Dietary spermidine improves cognitive function.Cell Reports. 2021;35(2):108985.doi:10.1016\/j.celrep.2021.108985<\/p>\n\n\n\n<p>5) Hofer SJ,et al.Mechanisms of spermidine-induced autophagy and geroprotection.Nature Aging.2022;2:1112\u20131129.doi:10.1038\/s43587-022-00322-9<\/p>\n\n\n\n<p>6) Eisenberg T, et al. Induction of autophagy by spermidine promotes longevity.Nature Cell Biology.2009;11:1305\u20131314.doi:10.1038\/ncb1975<\/p>\n\n\n\n<p>7) Kaeberlein M. Spermidine surprise for a long life.Nature Cell Biology.2009;11:1277\u20131278.doi:10.1038\/ncb1109-1277<\/p>\n\n\n\n<p>8) Kiechl S,et al.Higher spermidine intake is linked to lower mortality: a prospective population-basedstudy.American Journal of Clinical Nutrition.2018;108:371\u2013380.doi:10.1093\/ajcn\/nqy102<\/p>\n\n\n\n<p>9) \u6cbc\u53e3\u53cb\u6075,\u7af9\u4e2d\u60a0\u4eba,\u4f50\u85e4\u52c7\u7d00.\u30b9\u30da\u30eb\u30df\u30b8\u30f3\u542b\u6709\u9175\u6bcd\u300c\u30a8\u30ea\u30aa\u30f3SP\u300d\u306e\u6a5f\u80fd\u6027. Food Style 21.2023;27(10):45\u201348.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>1) \u4e95\u90e8\u660e\u5e83(2004)\u300c\u767a\u9175\u98df\u54c1\u306b\u542b\u307e\u308c\u308b\u30a2\u30df\u30f3\u985e\u300d\u6771\u4eac\u5065\u5b89\u7814\u30bb\u5e74\u583155, p.13-22 2) Madeo F,et.al.,Spermidine in health and disease.Science. 20 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":32,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/biopqq.jp\/yeast\/wp-json\/wp\/v2\/pages\/18"}],"collection":[{"href":"https:\/\/biopqq.jp\/yeast\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/biopqq.jp\/yeast\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/biopqq.jp\/yeast\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/biopqq.jp\/yeast\/wp-json\/wp\/v2\/comments?post=18"}],"version-history":[{"count":5,"href":"https:\/\/biopqq.jp\/yeast\/wp-json\/wp\/v2\/pages\/18\/revisions"}],"predecessor-version":[{"id":71,"href":"https:\/\/biopqq.jp\/yeast\/wp-json\/wp\/v2\/pages\/18\/revisions\/71"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopqq.jp\/yeast\/wp-json\/wp\/v2\/media\/32"}],"wp:attachment":[{"href":"https:\/\/biopqq.jp\/yeast\/wp-json\/wp\/v2\/media?parent=18"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}